There has been a possible advancement in the realm of male contraception. The two currently accessible contraceptives, vasectomy and condoms, will soon be joined by a third. When worn appropriately, condoms can effectively prevent sexually transmitted diseases (STDs). Vasectomy is a surgical procedure that has the potential to be reversed, although there is no assurance of this.
The new medication, called YCT-529, is an oral non-hormonal pill that was created in partnership with YourChoice Therapeutics, a biopharmaceutical business that is involved in clinical trials, and Columbia university in New York.
It functions by obstructing the sperm production pathway without interfering with testosterone levels.
According to a recent study on male mice and male monkeys that was published in Nature Medicine, fertility returned in the mice in 6 weeks and in the monkeys in 10 to 15 weeks.
In mice, this medication prevented pregnancies within 4 weeks of use, while in monkeys, it did so within 2 weeks of beginning treatment.
The phase-1 trial conducted on healthy males shows 99% efficiency and safety in humans, while the phase-2 trial, which is targeting men who have chosen vasectomy and those who do not wish to have children in the future, is currently in its early phases in New Zealand.
A novel gel known as NES/T was created last year to help men avoid getting pregnant. It contains the progestins testosterone and nestorone. The US Food and Drug Administration (FDA) needed to approve this.
Nearly half of pregnancies in the US and around the world are unplanned, which coincides with the current study.
The United Nations population Fund (UNFPA) research estimates that there were around 121 million unwanted pregnancies worldwide between 2015 and 2019.
Additionally, the study notes that the use of male contraceptives will contribute to a decrease in unwanted pregnancies and a reduction in gender disparity.
Men have two options for contraception, whereas women have several, including intrauterine devices, oral and emergency contraceptive tablets, and surgical alternatives.
If successful, this could transform male contraception by giving men reproductive autonomy and providing couples with more equal, reversible contraceptive options.
The new medication, called YCT-529, is an oral non-hormonal pill that was created in partnership with YourChoice Therapeutics, a biopharmaceutical business that is involved in clinical trials, and Columbia university in New York.
It functions by obstructing the sperm production pathway without interfering with testosterone levels.
According to a recent study on male mice and male monkeys that was published in Nature Medicine, fertility returned in the mice in 6 weeks and in the monkeys in 10 to 15 weeks.
In mice, this medication prevented pregnancies within 4 weeks of use, while in monkeys, it did so within 2 weeks of beginning treatment.
The phase-1 trial conducted on healthy males shows 99% efficiency and safety in humans, while the phase-2 trial, which is targeting men who have chosen vasectomy and those who do not wish to have children in the future, is currently in its early phases in New Zealand.
A novel gel known as NES/T was created last year to help men avoid getting pregnant. It contains the progestins testosterone and nestorone. The US Food and Drug Administration (FDA) needed to approve this.
Nearly half of pregnancies in the US and around the world are unplanned, which coincides with the current study.
The United Nations population Fund (UNFPA) research estimates that there were around 121 million unwanted pregnancies worldwide between 2015 and 2019.
Additionally, the study notes that the use of male contraceptives will contribute to a decrease in unwanted pregnancies and a reduction in gender disparity.
Men have two options for contraception, whereas women have several, including intrauterine devices, oral and emergency contraceptive tablets, and surgical alternatives.
If successful, this could transform male contraception by giving men reproductive autonomy and providing couples with more equal, reversible contraceptive options.
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